Identifying immune responses to human metapneumovirus
Official title: Discovery of human metapneumovirus epitopes
Funded at University of Wisconsin-Madison · NIH-11272118 · Data updated 2026-11-12
This study is looking at how our immune system reacts to a virus called human metapneumovirus, which can cause breathing problems, and it's for anyone interested in how we might create better vaccines to protect against this virus.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project start | August 21, 2024 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $174,938 |
| NIH project number | 7R21AI180460-02 |
| Project ID | NIH-11272118 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with a history of respiratory infections or those with underlying health conditions such as asthma or COPD.
✕Less likely to help
Patients who have not been infected with human metapneumovirus or those without any respiratory issues may not benefit from this research.
What this research studies
This research focuses on understanding how the immune system responds to human metapneumovirus (HMPV), a virus that causes respiratory infections. The team will identify specific parts of the virus that trigger T cell responses, which are crucial for fighting infections. By using specialized mice and human blood samples, they aim to discover which viral components are recognized by the immune system, which could help in developing effective vaccines. The research will involve screening various peptide pools to pinpoint the most relevant immune responses.
Why it matters
Potential benefit: If successful, this research could lead to the development of safer and more effective vaccines against human metapneumovirus.
How similar studies have gone: Previous research has shown success in identifying viral epitopes and their role in immune responses, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Wisconsin-Madison
Madison, United States Active
Researchers
- Principal investigator: Williams, John V. — University of Wisconsin-Madison
- Study coordinator: Williams, John V.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.