Identifying immune markers to predict outcomes in organ transplant patients with infections
Official title: Immune biomarkers to predict outcomes in solid organ transplant patients with bloodstream infections
Funded at Emory University · NIH-10807502 · Data updated 2026-11-12
This study is looking at organ transplant patients who are more likely to get serious bacterial infections, and it aims to find out how certain immune markers in their blood can help predict how severe these infections might be and how they could affect their health, so doctors can make better treatment choices for them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | August 2, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $196,344 |
| NIH project number | 1K23AI175676-01A1 |
| Project ID | NIH-10807502 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are solid organ transplant recipients who have experienced bacterial bloodstream infections.
✕Less likely to help
Patients who have not undergone solid organ transplantation or who do not have bacterial infections may not benefit from this research.
What this research studies
This research focuses on solid organ transplant recipients who are at a heightened risk for bacterial bloodstream infections. By analyzing existing biological samples, the study aims to identify specific immune biomarkers that can predict the severity of infections and potential mortality in these patients. The approach involves measuring levels of various immune-related substances and examining gene expression profiles to understand how the immune response affects clinical outcomes. Ultimately, the goal is to develop a prognostic model that can help guide treatment decisions for these vulnerable patients.
Why it matters
Potential benefit: If successful, this research could lead to improved prediction and management of infections in organ transplant patients, potentially reducing mortality rates.
How similar studies have gone: Previous research has shown promise in identifying immune biomarkers for infection outcomes, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Eichenberger, Emily M. — Emory University
- Study coordinator: Eichenberger, Emily M.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.