Identifying imaging markers to predict treatment response and recurrence in colorectal liver cancer
Official title: Development and Validation of Prognostic Radiomic Markers of Response and Recurrence for Patients with Colorectal Liver Metastases
Funded at Sloan-Kettering Inst Can Research · NIH-10684268 · Data updated 2026-11-12
This study is looking to find new ways to use regular CT scans to help predict how well patients with colorectal liver cancer will respond to treatment and their chances of the cancer coming back, so that doctors can tailor treatments to each person's needs.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | March 1, 2019 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $659,173 |
| NIH project number | 5R01CA233888-05 |
| Project ID | NIH-10684268 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with colorectal cancer who have developed liver metastases.
✕Less likely to help
Patients with colorectal cancer that has not metastasized to the liver may not benefit from this research.
What this research studies
This research aims to develop and validate non-invasive imaging markers that can predict how well patients with colorectal liver metastases will respond to treatment and their risk of recurrence. By analyzing routine CT scans, the study seeks to identify specific imaging features that correlate with treatment outcomes. The research involves collaboration with leading institutions to standardize imaging techniques and improve automated tools for clinical use. Ultimately, the goal is to enhance personalized treatment strategies for patients suffering from this aggressive form of cancer.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment plans for patients with colorectal liver metastases, improving survival rates.
How similar studies have gone: Previous research has shown promise in using imaging markers for predicting treatment outcomes in various cancers, suggesting that this approach could be effective.
Where this research is happening
-
Sloan-Kettering Inst Can Research
New York, United States Active
Researchers
- Principal investigator: Do, Richard Kinh Gian — Sloan-Kettering Inst Can Research
- Study coordinator: Do, Richard Kinh Gian
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.