NIH-funded research R01 grant

Identifying imaging markers to predict treatment response and recurrence in colorectal liver cancer

Official title: Development and Validation of Prognostic Radiomic Markers of Response and Recurrence for Patients with Colorectal Liver Metastases

Funded at Sloan-Kettering Inst Can Research · NIH-10684268 · Data updated 2026-11-12

This study is looking to find new ways to use regular CT scans to help predict how well patients with colorectal liver cancer will respond to treatment and their chances of the cancer coming back, so that doctors can tailor treatments to each person's needs.

More Recurrence research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionSloan-Kettering Inst Can Research
NIH-funded
Lab location1 site (New York, United States)
Project startMarch 1, 2019
Project endAugust 31, 2025
Funding year2023
Award (this year)$659,173
NIH project number5R01CA233888-05
Project IDNIH-10684268 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are patients diagnosed with colorectal cancer who have developed liver metastases.

Less likely to help

Patients with colorectal cancer that has not metastasized to the liver may not benefit from this research.

What this research studies

This research aims to develop and validate non-invasive imaging markers that can predict how well patients with colorectal liver metastases will respond to treatment and their risk of recurrence. By analyzing routine CT scans, the study seeks to identify specific imaging features that correlate with treatment outcomes. The research involves collaboration with leading institutions to standardize imaging techniques and improve automated tools for clinical use. Ultimately, the goal is to enhance personalized treatment strategies for patients suffering from this aggressive form of cancer.

Why it matters

Potential benefit: If successful, this research could lead to more effective and personalized treatment plans for patients with colorectal liver metastases, improving survival rates.

How similar studies have gone: Previous research has shown promise in using imaging markers for predicting treatment outcomes in various cancers, suggesting that this approach could be effective.

Where this research is happening

  • Sloan-Kettering Inst Can Research
    New York, United States
    Active

Researchers

  • Principal investigator: Do, Richard Kinh Gian — Sloan-Kettering Inst Can Research
  • Study coordinator: Do, Richard Kinh Gian

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.