Identifying imaging markers to predict Alzheimer's disease from mild cognitive impairment
Identification of Multi-modal Imaging Biomarkers for Early Prediction of MCI-AD Conversion via Multigraph Representation
This study is looking for better ways to predict when someone with mild cognitive impairment might develop Alzheimer's disease, using advanced brain scans and technology, so that patients can get help earlier to manage their symptoms.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10510971 on NIH RePORTER |
What this research studies
This research focuses on finding effective ways to predict the conversion from mild cognitive impairment (MCI) to Alzheimer's disease (AD) using advanced imaging techniques. By analyzing various neuroimaging data, the study aims to identify specific biomarkers that can indicate the likelihood of this conversion. The approach utilizes deep learning methods to enhance the accuracy of predictions and improve the understanding of brain changes associated with these conditions. Patients may benefit from early identification and management strategies that could slow the progression of cognitive decline.
Who could benefit from this research
Good fit: Ideal candidates for this research are elderly individuals diagnosed with mild cognitive impairment.
Not a fit: Patients who are already diagnosed with Alzheimer's disease or other forms of dementia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier interventions for patients at risk of developing Alzheimer's disease.
How similar studies have performed: Previous research has shown promise in using multi-modal imaging techniques for predicting Alzheimer's disease, indicating that this approach has potential for success.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Li, Xiang — Massachusetts General Hospital
- Study coordinator: Li, Xiang
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.