Identifying imaging biomarkers for coronary microcirculation health
Official title: Angiography-derived Imaging Biomarkers of the Coronary Microcirculation
Funded at University of Pennsylvania · NIH-11030251 · Data updated 2026-11-12
This study is looking at how well the tiny blood vessels in your heart are working, using special imaging techniques to gather important information that could help improve care for heart conditions like ischemic heart disease.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | February 7, 2024 |
| Project end | January 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $203,125 |
| NIH project number | 5R21EB035382-02 |
| Project ID | NIH-11030251 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with ischemic heart disease or those at risk for coronary microvascular dysfunction.
✕Less likely to help
Patients with conditions unrelated to coronary microcirculation or those who do not undergo imaging procedures may not benefit from this research.
What this research studies
This research focuses on improving the understanding of the coronary microcirculation, which is crucial for heart health. By analyzing existing imaging data, the researchers aim to identify specific characteristics of microvascular function without needing to directly visualize the smallest blood vessels. The study will utilize advanced image analysis techniques to extract valuable information from time-course data of contrast material in blood vessels and surrounding tissues. This approach could lead to better assessments of heart conditions, particularly ischemic heart disease.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic methods for assessing coronary microcirculation, potentially enhancing treatment strategies for heart disease.
How similar studies have gone: Previous research has shown promise in using imaging data to assess vascular health, suggesting that this approach may yield valuable insights.
Where this research is happening
-
University of Pennsylvania
Philadelphia, United States Active
Researchers
- Principal investigator: Guerraty, Marie a — University of Pennsylvania
- Study coordinator: Guerraty, Marie a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.