Identifying how certain proteins interact with kinases in the body
Multi-modal data integration to identify kinase substrates
This study is looking at how certain proteins called kinases interact with other molecules in the body, which could help us understand diseases like cancer and brain disorders better, ultimately leading to better treatment options for patients.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10659156 on NIH RePORTER |
What this research studies
This research focuses on understanding the interactions between kinases, which are proteins that play crucial roles in various bodily functions, and their substrates, which are the molecules they act upon. By utilizing advanced computational methods and integrating diverse biological data, the project aims to predict these interactions more accurately. This could lead to better insights into diseases like cancer and central nervous system disorders, where kinase dysregulation is a key factor. Patients may benefit from improved treatment options as a result of this research.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with cancers or central nervous system disorders who may benefit from targeted therapies.
Not a fit: Patients with conditions unrelated to kinase dysregulation or those not diagnosed with cancer or CNS disorders may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of more effective therapies for cancers and central nervous system disorders.
How similar studies have performed: Other research has shown success in using computational methods to predict protein interactions, indicating that this approach has potential for meaningful advancements.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Pandey, Gaurav — Icahn School of Medicine at Mount Sinai
- Study coordinator: Pandey, Gaurav
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.