Identifying how antibodies protect against certain viral infections
Official title: B cell Epitope Discovery and Mechanisms of Antibody Protection for Enterovirus and Bunyavirus Entry Proteins
Funded at Integral Molecular · NIH-11196677 · Data updated 2026-11-12
This study is looking at how our immune system's antibodies recognize certain parts of Enterovirus and Bunyavirus, which could help create better vaccines and treatments for everyone.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Integral Molecular NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | September 16, 2024 |
| Project end | September 15, 2025 |
| Funding year | 2024 |
| Award (this year) | $1,569,483 |
| NIH project number | 75N93024C00071-0-9999-1 |
| Project ID | NIH-11196677 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit would include individuals at risk for infections caused by Enterovirus and Bunyavirus.
✕Less likely to help
Patients with infections caused by other viruses not targeted by this research may not receive any benefit.
What this research studies
This research aims to discover specific parts of viruses that antibodies recognize, which is crucial for understanding how our immune system fights infections. By focusing on Enterovirus and Bunyavirus, the study will explore how these antibody interactions can lead to better vaccines and treatments. Patients may benefit from advancements in vaccine development and new therapies that arise from this research, as it seeks to enhance our understanding of immune responses to these viruses.
Why it matters
Potential benefit: If successful, this research could lead to improved vaccines and therapies for viral infections.
How similar studies have gone: Previous research has shown success in identifying antibody epitopes leading to advancements in vaccine development, suggesting this approach has potential.
Where this research is happening
-
Integral Molecular
Philadelphia, United States Active
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.