Identifying high-risk patients with interstitial lung abnormalities
Official title: Risk-stratification and prediction of adverse outcomes in interstitial lung abnormalities
Funded at Brigham and Women's Hospital · NIH-11057656 · Data updated 2026-11-12
This study is looking at lung issues that could lead to serious problems like pulmonary fibrosis, and it's for people with these lung abnormalities; the goal is to find out who might be at greater risk so that doctors can step in early and help improve their treatment.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | April 1, 2024 |
| Project end | March 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $167,410 |
| NIH project number | 5K08HL173562-02 |
| Project ID | NIH-11057656 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults with interstitial lung abnormalities who may be at risk for developing pulmonary fibrosis.
✕Less likely to help
Patients with established pulmonary fibrosis or those without interstitial lung abnormalities may not benefit from this research.
What this research studies
This research focuses on understanding interstitial lung abnormalities (ILA) that can lead to pulmonary fibrosis, a serious lung condition. The team aims to develop methods to predict which patients with ILA are at higher risk for adverse outcomes, using advanced imaging techniques and clinical data. By identifying these high-risk patients, the research seeks to facilitate early intervention and improve treatment outcomes. The study will also explore novel biomarkers to enhance risk stratification and better understand the disease mechanisms.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and treatment options for patients at risk of developing pulmonary fibrosis.
How similar studies have gone: Previous research has shown promise in using imaging and clinical data to predict outcomes in similar patient populations, indicating a potential for success in this approach.
Where this research is happening
-
Brigham and Women's Hospital
Boston, United States Active
Researchers
- Principal investigator: Rose, Jonathan — Brigham and Women's Hospital
- Study coordinator: Rose, Jonathan
Related research
Other NIH-funded projects on the same topics.
-
Targeted therapies for glioblastoma in adults and kids
A large NIH program is exploring new brain cancer therapies, including drugs that reach the brain and work against glioblastoma in both children and adults.
-
Statins to Prevent Cancer-Associated Blood Clots in Cancer Patients
A large study will test whether taking rosuvastatin every day for a year can lower the chance of dangerous blood clots in people with cancer, without raising the risk of bleeding.
-
Preterm infant body composition and early-life health after NICU stay
This grant studies how body composition in very preterm babies relates to later brain development and risk of obesity or diabetes, with findings meant to improve care from NICU through early childhood.
-
Rapid Emergency Skills for Prehospital Optimization and Delivery (RESPOND) for Guatemala
A lightweight, AI-enabled prehospital training and triage program helps volunteer firefighters in Guatemala deliver faster, better care to trauma patients.
-
Rapid Emergency Skills for Prehospital Optimization and Notification in Guatemala
A mobile, AI-powered training and triage program helps volunteer emergency responders in Guatemala provide faster, safer trauma care and notify hospitals more quickly.
-
Understanding antibiotic allergy to improve care for patients
Scientists are testing new ideas to understand why some people develop severe allergic reactions to antibiotics and how to prevent or treat them.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.