Identifying high-risk chronic kidney disease using non-invasive imaging techniques
Non-Invasive Imaging Biomarkers to Identify a High-Risk Chronic Kidney Disease Phenotype
This study is looking at how a special type of ultrasound can help find out which people with chronic kidney disease are more likely to face serious problems, like heart issues or kidney failure, so we can avoid risky kidney biopsies and improve treatment options for them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Illinois at Chicago NIH-funded |
| Lab location | 1 site (Chicago, UNITED STATES) |
| Project ID | NIH-10783826 on NIH RePORTER |
What this research studies
This research investigates how non-invasive imaging can help identify patients with chronic kidney disease (CKD) who are at high risk for serious complications, such as cardiovascular disease and kidney failure. By using contrast-enhanced ultrasound to assess renal microvascular perfusion, the study aims to provide a safer alternative to kidney biopsies, which can carry risks. The research will evaluate how well these imaging techniques correlate with traditional measures of kidney function and health, potentially leading to better patient selection for clinical trials and treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with chronic kidney disease, particularly those showing signs of advanced disease or severe histopathologic lesions.
Not a fit: Patients with early-stage chronic kidney disease or those without significant histopathologic findings may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved identification of high-risk CKD patients, allowing for earlier interventions and better management of their condition.
How similar studies have performed: Previous studies have shown promising results using similar imaging techniques, suggesting that this approach may be effective in identifying high-risk patients.
Where this research is happening
Chicago, UNITED STATES
- University of Illinois at Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Srivastava, Anand — University of Illinois at Chicago
- Study coordinator: Srivastava, Anand
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.