Identifying heart issues caused by premature ventricular contractions.
Official title: Imaging-based Indentification of Premature Ventricular Contraction-mediated
Funded at Ohio State University · NIH-11095956 · Data updated 2026-11-12
This study is looking at how premature heartbeats, called PVCs, might affect heart health, especially in people with different heart conditions, and it aims to help doctors better understand and manage these heartbeats using special heart imaging techniques.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | April 8, 2020 |
| Project end | March 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $451,241 |
| NIH project number | 5R01HL148103-05 |
| Project ID | NIH-11095956 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals experiencing frequent premature ventricular contractions, particularly those with or without structural heart disease.
✕Less likely to help
Patients who do not experience premature ventricular contractions or have other unrelated heart conditions may not benefit from this research.
What this research studies
This research investigates the effects of premature ventricular contractions (PVCs) on heart function, particularly how they may lead to cardiomyopathy in patients with normal and abnormal heart structures. Using advanced cardiac magnetic resonance imaging (MRI), the study aims to differentiate between benign and pathologic PVCs by assessing left ventricular function during these contractions. The research will involve monitoring patients with varying PVC burdens to understand the relationship between PVCs and heart health over time. By analyzing these factors, the study seeks to provide insights into the risks associated with PVCs and improve patient management strategies.
Why it matters
Potential benefit: If successful, this research could lead to better diagnosis and treatment options for patients experiencing PVCs, potentially reducing the risk of serious heart conditions.
How similar studies have gone: Previous research has shown that understanding the impact of PVCs on heart function can lead to significant advancements in treatment, but this specific approach using advanced MRI techniques is relatively novel.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Han, Yuchi — Ohio State University
- Study coordinator: Han, Yuchi
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.