Identifying glycan biomarkers for cholangiocarcinoma
Glycan Biomarkers for Cholangiocarcinoma
['FUNDING_R01'] · MEDICAL UNIVERSITY OF SOUTH CAROLINA · NIH-11049609
This study is looking at how certain changes in sugars found in blood and tissue can help doctors spot bile duct cancer earlier and tell it apart from other illnesses, with the hope of improving diagnosis and treatment for patients.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MEDICAL UNIVERSITY OF SOUTH CAROLINA (nih funded) |
| Locations | 1 site (CHARLESTON, UNITED STATES) |
| Trial ID | NIH-11049609 on ClinicalTrials.gov |
What this research studies
This research focuses on cholangiocarcinoma, a lethal cancer affecting the bile ducts. It aims to identify specific glycan changes in tissue and serum that could serve as biomarkers for early detection and differentiation from other diseases. By analyzing these glycan alterations, the research seeks to improve diagnostic accuracy and potentially enhance treatment outcomes for patients. The approach involves studying both serum and tissue samples to establish a reliable biomarker panel.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at risk for cholangiocarcinoma or those presenting with symptoms suggestive of biliary cancer.
Not a fit: Patients with other types of cancers unrelated to biliary structures may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate diagnosis of cholangiocarcinoma, improving patient outcomes.
How similar studies have performed: Previous research has shown promise in using glycan biomarkers for cancer detection, suggesting potential success for this approach.
Where this research is happening
CHARLESTON, UNITED STATES
- MEDICAL UNIVERSITY OF SOUTH CAROLINA — CHARLESTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MEHTA, ANAND S. — MEDICAL UNIVERSITY OF SOUTH CAROLINA
- Study coordinator: MEHTA, ANAND S.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Bile Duct Diseases, biliary cancer