Identifying genetic markers to predict lung cancer recurrence
Official title: Proteogenomic Predictors of Recurrence in Non-small Cell Lung Cancer
Funded at Washington University · NIH-11098690 · Data updated 2026-11-12
This study is looking at the genes in early-stage non-small cell lung cancer to find clues that might help predict if the cancer will come back after surgery, and if you join, you could help improve future treatments for lung cancer.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | June 13, 2022 |
| Project end | May 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $803,945 |
| NIH project number | 5U01CA271402-04 |
| Project ID | NIH-11098690 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with early-stage non-small cell lung cancer who have undergone surgical resection.
✕Less likely to help
Patients with advanced-stage lung cancer or those who have not undergone surgery may not benefit from this research.
What this research studies
This research investigates the genetic and molecular characteristics of non-small cell lung cancer (NSCLC) to identify biomarkers that can predict the likelihood of cancer recurrence after surgery. By analyzing tumor samples from patients with early-stage NSCLC, the study aims to uncover specific genetic mutations and alterations that may indicate a higher risk of metastatic disease. Patients who participate may undergo genetic testing and contribute to a larger effort to improve treatment strategies for lung cancer. The findings could lead to more personalized treatment plans based on individual tumor profiles.
Why it matters
Potential benefit: If successful, this research could lead to improved prediction of cancer recurrence, allowing for more tailored and effective treatment options for lung cancer patients.
How similar studies have gone: Previous research has shown promise in identifying genetic markers for cancer recurrence, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Govindan, Ramaswamy — Washington University
- Study coordinator: Govindan, Ramaswamy
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.