Identifying genetic markers for preeclampsia risk in mothers with high blood pressure
Epigenetic biomarkers of preeclampsia risk among mothers with chronic hypertension
This study is looking at how certain genetic changes in your blood can help predict if you might develop preeclampsia during pregnancy if you already have high blood pressure, so that doctors can keep a closer eye on you and provide better care for you and your baby.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project ID | NIH-11007261 on NIH RePORTER |
What this research studies
This research investigates how certain genetic changes, known as epigenetic biomarkers, can indicate the risk of developing preeclampsia in pregnant women who have chronic hypertension. By analyzing blood samples from these mothers, the study aims to identify specific markers that could help predict the onset of preeclampsia earlier in pregnancy. This early identification could lead to improved monitoring and treatment options, ultimately enhancing maternal and fetal health outcomes. The research focuses on understanding the biological mechanisms behind preeclampsia to develop better preventative strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant women with a history of chronic hypertension.
Not a fit: Patients who are not pregnant or do not have chronic hypertension may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and better management of preeclampsia, reducing risks for both mothers and their babies.
How similar studies have performed: Previous studies have shown promise in using epigenetic markers for predicting pregnancy complications, suggesting that this approach may be effective.
Where this research is happening
Birmingham, United States
- University of Alabama at Birmingham — Birmingham, United States (Active)
Researchers
- Principal investigator: Hidalgo, Bertha — University of Alabama at Birmingham
- Study coordinator: Hidalgo, Bertha
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.