Identifying genetic factors that increase breast cancer risk
Official title: DCEG- GWAS Studies
Funded at Leidos Biomedical Research, INC. · NIH-11219745 · Data updated 2026-11-12
This study is looking at how certain inherited genes might increase the risk of breast cancer, and it's for anyone interested in understanding more about the genetic factors that could help improve prevention and treatment options for this condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Leidos Biomedical Research, INC. NIH-funded |
| Lab location | 1 site (Frederick, United States) |
| Project start | September 28, 2024 |
| Project end | August 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $2,881,737 |
| NIH project number | 75N91019D00024-0-759102400011-3 |
| Project ID | NIH-11219745 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with a family history of breast cancer or those who have been diagnosed with breast cancer.
✕Less likely to help
Patients without a genetic predisposition to breast cancer or those with unrelated health conditions may not benefit from this research.
What this research studies
This research investigates inherited genetic factors that may contribute to the risk of developing breast cancer through genome-wide association studies (GWAS). By analyzing DNA from individuals involved in various cancer studies, researchers aim to identify common genetic variants linked to cancer susceptibility. The project collaborates with external scientists and utilizes large data sets to enhance the understanding of gene-environment interactions. The findings could lead to improved prevention, diagnosis, and treatment strategies for breast cancer.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing and treating breast cancer based on genetic risk factors.
How similar studies have gone: Previous studies using similar genome-wide association approaches have successfully identified genetic markers associated with various cancers, indicating a promising avenue for this research.
Where this research is happening
-
Leidos Biomedical Research, INC.
Frederick, United States Active
Researchers
- Principal investigator: Briscoe, Lynn — Leidos Biomedical Research, INC.
- Study coordinator: Briscoe, Lynn
Related research
Other NIH-funded projects on the same topics.
-
Improving public health responses to COVID-19 through standardized testing.
This study is looking to improve how we fight COVID-19 by testing blood samples to see if people have had the virus, and it’s designed for anyone interested in better ways to manage the disease.
-
Creating a large library of cancer models for research use
This study is creating a collection of new cancer models to help researchers and companies find better ways to treat cancer, making it easier for everyone to work together and share ideas.
-
Advancing global cancer control through data analysis and international collaboration
This study is all about helping countries around the world work better together to fight cancer by sharing important information and training scientists, especially in places that need extra support.
-
Support for HIV and HPV cancer prevention clinical trials in the Americas
This study is working on new vaccines and treatments to help prevent cancers related to HIV and HPV, making sure that patients in the US, Latin America, and the Caribbean can access better options as these exciting trials move forward.
-
Development and production of clinical-grade biopharmaceuticals
This study is all about making safe and effective new medicines, like vaccines and treatments for various conditions, so that patients can have access to the latest therapies that meet high-quality standards.
-
Understanding the immune response to COVID-19
This study is looking for ways to improve COVID-19 testing and understand how our immune system fights the virus, and you can help by sharing samples to make these tests better for everyone.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.