Identifying genetic factors linked to substance use disorders
Functional genetic variants in substance use disorders
This study is looking at how certain genetic differences might influence substance use disorders, helping us understand the biology behind these issues so we can find better ways to prevent and treat them.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Indiana University Indianapolis NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project ID | NIH-10892854 on NIH RePORTER |
What this research studies
This research aims to uncover genetic variants that contribute to substance use disorders (SUDs) by examining how these variants affect gene regulation. Researchers will use advanced experimental methods and computational models to analyze thousands of genetic variations in brain cells, including neurons and astrocytes. By understanding these genetic influences, the study seeks to provide insights into the biological mechanisms behind SUDs, potentially leading to improved prevention and treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with a history of substance use disorders or those at risk due to genetic factors.
Not a fit: Patients without any history of substance use disorders or those not genetically predisposed may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for individuals struggling with substance use disorders.
How similar studies have performed: Previous research has shown promise in identifying genetic factors related to substance use disorders, suggesting that this approach could yield valuable insights.
Where this research is happening
Indianapolis, United States
- Indiana University Indianapolis — Indianapolis, United States (Active)
Researchers
- Principal investigator: Edenberg, Howard J — Indiana University Indianapolis
- Study coordinator: Edenberg, Howard J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.