Identifying genetic factors linked to rotator cuff tears and healing
Official title: Determining Genetic Variants Associated with Rotator Cuff Tearing, Tear Progression and Tendon Repair Healing
Funded at VA Salt Lake City Healthcare System · NIH-10914393 · Data updated 2026-11-12
This study is looking at how certain genes might affect the risk of rotator cuff tears and how well they heal after surgery, especially for people with a family history of these injuries.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | VA Salt Lake City Healthcare System NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project start | April 1, 2025 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| NIH project number | 1I01CX002571-01A1 |
| Project ID | NIH-10914393 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with a history of rotator cuff tears, particularly those with a family history of such injuries or specific genetic markers.
✕Less likely to help
Patients without a history of rotator cuff injuries or those who do not have identifiable genetic variants related to rotator cuff tearing may not benefit from this research.
What this research studies
This research investigates the genetic variants that may contribute to the risk of rotator cuff tears and the healing process after tendon repair. By analyzing genetic data from large databases, the study aims to uncover how specific genetic markers are associated with the severity of rotator cuff injuries and the likelihood of successful healing. Patients with a family history of rotator cuff issues or specific genetic variants may be particularly relevant to this research. The goal is to enhance understanding of rotator cuff injuries and improve treatment outcomes.
Why it matters
Potential benefit: If successful, this research could lead to personalized treatment strategies for patients with rotator cuff tears based on their genetic profiles.
How similar studies have gone: Previous research has successfully identified genetic variants associated with other musculoskeletal conditions, suggesting a promising avenue for this type of investigation.
Where this research is happening
-
VA Salt Lake City Healthcare System
Salt Lake City, United States Active
Researchers
- Principal investigator: Tashjian, Robert Z — VA Salt Lake City Healthcare System
- Study coordinator: Tashjian, Robert Z
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.