Identifying genetic factors linked to opioid use disorder in rats
Identification of genes and genetic networks contributing to opioid use disorder traits in the Hybrid Rat Diversity Panel
This study is looking at how genes might influence opioid addiction by observing different types of rats and their reactions to oxycodone, which could help us understand addiction better and find new ways to treat it.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado NIH-funded |
| Lab location | 1 site (Boulder, UNITED STATES) |
| Project ID | NIH-10854823 on NIH RePORTER |
What this research studies
This research investigates the genetic basis of opioid use disorder by studying various rat strains. Using a genetic model, the project aims to identify how different genes and genetic networks contribute to behaviors associated with opioid addiction, particularly focusing on oxycodone. The researchers will assess behavioral responses to oxycodone and analyze genetic data to pinpoint specific traits linked to addiction risk. This approach may help uncover the biological mechanisms behind opioid use disorders, potentially leading to better treatment options.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research would be individuals struggling with opioid use disorder or at risk for developing such conditions.
Not a fit: Patients who do not have a history of opioid use or are not at risk for opioid use disorder may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment strategies for opioid use disorders in humans.
How similar studies have performed: Other research has shown promise in using genetic models to understand addiction, suggesting that this approach could yield valuable insights.
Where this research is happening
Boulder, UNITED STATES
- University of Colorado — Boulder, United States (Active)
Researchers
- Principal investigator: Ehringer, Marissa a — University of Colorado
- Study coordinator: Ehringer, Marissa a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.