Identifying genetic factors in familial lung cancer
Sequencing Familial Lung Cancer
This study is looking at how genetics might play a role in lung cancer, especially for families who have a lot of cases, to help find out what changes in genes can increase the risk and improve ways to screen and prevent the disease for those at risk.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10788313 on NIH RePORTER |
What this research studies
This research investigates the genetic factors that contribute to lung cancer, particularly in families with a strong history of the disease. By analyzing samples and data collected over 20 years from individuals with familial lung cancer, the study aims to uncover specific genetic mutations and alterations that increase the risk of developing lung cancer. The research will utilize advanced genetic sequencing techniques to identify these factors and understand how they influence cancer risk, potentially leading to improved screening and prevention strategies for at-risk individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with a strong family history of lung cancer, particularly those with multiple relatives affected by the disease.
Not a fit: Patients without a family history of lung cancer or those with sporadic cases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better identification of individuals at high risk for lung cancer, allowing for earlier screening and preventive measures.
How similar studies have performed: Previous research has shown success in identifying genetic factors associated with other cancers, suggesting that this approach may yield valuable insights for lung cancer as well.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Liu, Yanhong — Baylor College of Medicine
- Study coordinator: Liu, Yanhong
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.