Identifying genetic and immune factors for asthma and allergies
Integrated genetic, omic, and immunologic studies to identify endotypes and novel drug targets for asthma and allergic diseases
This study is looking at the genes and immune system factors that cause asthma and allergies to find new ways to treat these conditions, so patients can get more personalized care based on their unique biology.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-11077765 on NIH RePORTER |
What this research studies
This research investigates the genetic and immunologic underpinnings of asthma and allergic diseases to identify specific endotypes and potential new drug targets. By analyzing genetic variants and their effects on various immune and lung cell types, the research aims to uncover the biological mechanisms that contribute to these conditions. Patients may benefit from a more personalized approach to treatment based on their unique genetic and immunologic profiles. The study employs advanced statistical and molecular tools to bridge the gap between genetic findings and practical therapies.
Who could benefit from this research
Good fit: Ideal candidates for participation include individuals of all ages suffering from asthma or allergic diseases.
Not a fit: Patients with non-allergic respiratory conditions or those without asthma or allergic diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and targeted treatments for asthma and allergic diseases.
How similar studies have performed: Previous research has shown promise in identifying genetic factors related to asthma and allergies, but this approach aims to provide deeper insights and novel targets.
Where this research is happening
Chicago, United States
- University of Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Ober, Carole — University of Chicago
- Study coordinator: Ober, Carole
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.