Identifying genes that increase the risk of autism and their effects on the disorder
1/4 - The Autism Sequencing Consortium: Discovering autism risk genes and how they impact core features of the disorder
This study is looking at the genes of people with autism and their families to find out how certain genetic changes might be linked to autism, which could help us understand the condition better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11007222 on NIH RePORTER |
What this research studies
This research investigates the genetic factors associated with autism spectrum disorder (ASD) by analyzing DNA from individuals with ASD and their families. The Autism Sequencing Consortium is a collaborative effort that aims to identify risk genes and understand how they influence the core features of autism. By examining various types of genetic variations, including rare mutations, the research seeks to uncover insights into the biological pathways affected in ASD. This could lead to a better understanding of the disorder and its underlying mechanisms.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with autism spectrum disorder and their family members.
Not a fit: Patients without a diagnosis of autism spectrum disorder or those who do not have a family history of ASD may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of autism and potentially lead to improved diagnostic and therapeutic strategies for individuals with ASD.
How similar studies have performed: Previous research has successfully identified genetic factors associated with autism, indicating that this approach has the potential for significant findings.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Buxbaum, Joseph D. — Icahn School of Medicine at Mount Sinai
- Study coordinator: Buxbaum, Joseph D.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.