Identifying genes that increase the risk of autism and their effects on the disorder
2/4 The Autism Sequencing Consortium: Discovering autism risk genes and how they impact core features of the disorder
This study is looking at the genes that might play a role in autism spectrum disorder (ASD) to help us understand how they affect the condition, and it’s for individuals and families impacted by ASD who want to learn more about the genetic factors involved.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Broad Institute, INC. NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project ID | NIH-11006325 on NIH RePORTER |
What this research studies
This research investigates the genetic factors that contribute to autism spectrum disorder (ASD) by analyzing genetic variations in individuals and families affected by ASD. The study focuses on identifying specific genes associated with autism risk and understanding how these genes influence the core features of the disorder. By examining a large dataset of over 72,000 individuals, the research aims to uncover rare genetic variations that may play a significant role in the development of ASD. Patients may benefit from insights into the genetic underpinnings of their condition, which could lead to more personalized approaches to treatment and support.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with autism spectrum disorder and their families.
Not a fit: Patients with autism spectrum disorder who do not have a genetic component to their condition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of autism spectrum disorder through targeted interventions based on genetic insights.
How similar studies have performed: Previous research has successfully identified genetic factors associated with autism, indicating that this approach has potential for further discoveries.
Where this research is happening
Cambridge, United States
- Broad Institute, INC. — Cambridge, United States (Active)
Researchers
- Principal investigator: Daly, Mark Joseph — Broad Institute, INC.
- Study coordinator: Daly, Mark Joseph
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.