Identifying genes that help protect newborns from respiratory issues.
An in vivo screen for genes underlying protective neonate respiratory reflexes to identify potential contributors to Sudden Infant Death Syndrome and other congenital respiratory pathophysiologies
This study is looking at the genes that help newborns breathe properly, especially since problems with these reflexes can be linked to Sudden Infant Death Syndrome (SIDS), and the goal is to find ways to improve respiratory health in babies.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11004351 on NIH RePORTER |
What this research studies
This research aims to uncover the genetic factors that contribute to essential respiratory reflexes in newborns, which may be disrupted in conditions like Sudden Infant Death Syndrome (SIDS). By utilizing advanced genetic techniques, the study will analyze specific mouse models to identify genes critical for the development and function of these protective reflexes. The findings could lead to a better understanding of respiratory disorders in infants and inform potential interventions. Patients may benefit from insights gained regarding the genetic underpinnings of respiratory health in neonates.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research are infants under one year of age, particularly those at risk for respiratory disorders.
Not a fit: Patients who are older than one year or do not have respiratory issues may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention strategies and treatments for respiratory issues in infants, potentially reducing the incidence of SIDS.
How similar studies have performed: Previous research has shown promise in identifying genetic factors related to respiratory reflexes, suggesting that this approach could yield valuable insights.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Ray, Russell S — Baylor College of Medicine
- Study coordinator: Ray, Russell S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.