Identifying genes linked to brain malformations in children
Official title: Brain Malformation Expert Panels for Gene and Variant Curation
Funded at Boston Children's Hospital · NIH-11076791 · Data updated 2026-11-12
This study is working to gather and organize information about genes linked to brain malformations in children, so doctors can better understand and treat these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Children's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | May 1, 2024 |
| Project end | April 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $377,718 |
| NIH project number | 5U24NS137481-02 |
| Project ID | NIH-11076791 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 0-11 years who have been diagnosed with brain malformations or related neurological disorders.
✕Less likely to help
Patients with brain malformations caused by non-genetic factors may not benefit from this research.
What this research studies
This research aims to create a comprehensive resource that categorizes and curates genes and genetic variants associated with brain malformations in children. An expert panel of clinicians and researchers will review existing literature to identify and evaluate the evidence for these genetic links. The goal is to enhance the understanding of brain malformations, which can lead to better diagnosis and management strategies for affected children. By organizing this information, the research seeks to provide valuable insights for healthcare providers treating these conditions.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnosis and treatment options for children with brain malformations.
How similar studies have gone: Previous research has successfully identified genetic links to various brain disorders, indicating that this approach has potential for significant findings.
Where this research is happening
-
Boston Children's Hospital
Boston, United States Active
Researchers
- Principal investigator: Olson, Heather Elisa — Boston Children's Hospital
- Study coordinator: Olson, Heather Elisa
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.