Identifying genes linked to Alzheimer's disease and their role in cellular processes
Identification of AD-risk genes affecting endolysosomal and lipid homeostasis pathways
This study is looking at how certain genes might influence the development of Alzheimer's disease, with the hope that understanding these genetic factors can help find new ways to treat or prevent the condition early on.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Regenerative Research Foundation NIH-funded |
| Lab location | 1 site (Albany, UNITED STATES) |
| Project ID | NIH-11124487 on NIH RePORTER |
What this research studies
This research investigates the genetic factors that contribute to Alzheimer's disease, focusing on how certain genes affect the endolysosomal and lipid homeostasis pathways in cells. By analyzing data from a collaborative consortium, the study aims to identify key risk genes that may play a role in the early development of Alzheimer's. Patients may benefit from insights gained through this research, which could lead to new strategies for early intervention and treatment. The approach includes genome-wide association studies and functional analyses to understand the genetic underpinnings of Alzheimer's.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a family history of Alzheimer's disease or those showing early signs of cognitive decline.
Not a fit: Patients with advanced Alzheimer's disease or those without any genetic predisposition to the condition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to early interventions that slow or prevent the onset of Alzheimer's disease.
How similar studies have performed: Previous studies have shown success in identifying genetic risk factors for Alzheimer's disease, suggesting that this approach has the potential for meaningful advancements.
Where this research is happening
Albany, UNITED STATES
- Regenerative Research Foundation — Albany, United States (Active)
Researchers
- Principal investigator: Temple, Sally — Regenerative Research Foundation
- Study coordinator: Temple, Sally
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.