Identifying genes and risk factors for Alzheimer's disease
Discovering causal genes, brain regions and other risk factors for Alzheimer'a disease
This study is looking at how our genes and environment might play a role in Alzheimer's disease, with the goal of finding ways to help prevent it, so that people at risk can get better support and care.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-10775736 on NIH RePORTER |
What this research studies
This research investigates the genetic and environmental factors that contribute to Alzheimer's disease (AD). By utilizing advanced causal inference methods and large-scale genetic data, the study aims to identify specific genes and brain regions associated with AD. The approach includes analyzing existing genetic studies to determine causal relationships and potential interventions that could reduce the incidence of AD. Patients may benefit from insights that could lead to targeted prevention strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for Alzheimer's disease, such as those with a family history or early signs of cognitive decline.
Not a fit: Patients with advanced Alzheimer's disease or those who do not have any genetic or lifestyle risk factors for the disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or delaying the onset of Alzheimer's disease.
How similar studies have performed: Previous research has shown success in identifying genetic risk factors for Alzheimer's disease using similar methodologies, indicating a promising avenue for further exploration.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Pan, Wei — University of Minnesota
- Study coordinator: Pan, Wei
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.