Identifying gene networks related to opioid addiction
Multi-omics Gene Network Identification (Project 4)
This study is looking at how our genes might play a role in opioid addiction, using information from both people and animals to help find better treatments for those struggling with this issue.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Research Triangle Institute NIH-funded |
| Lab location | 1 site (Research Triangle Park, United States) |
| Project ID | NIH-11086869 on NIH RePORTER |
What this research studies
This research aims to uncover the genetic networks that contribute to opioid addiction by using a comprehensive approach called Gene Network Identification and Integration (GNetII). By analyzing data from both human subjects and animal models, the researchers will integrate various types of genetic information, including genome-wide association studies and gene regulation data from brain tissues. This multi-omics framework allows for a deeper understanding of the biological mechanisms behind opioid addiction, which could lead to more effective treatments. The study focuses on understanding how genetic factors influence addiction, particularly in the context of the brain's response to opioids.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 21 and older who are affected by opioid addiction or related disorders.
Not a fit: Patients who are not affected by opioid addiction or are under the age of 21 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights and treatments for individuals struggling with opioid addiction.
How similar studies have performed: Previous research has shown promise in using multi-omics approaches to understand complex disorders, suggesting that this method could yield valuable insights into opioid addiction.
Where this research is happening
Research Triangle Park, United States
- Research Triangle Institute — Research Triangle Park, United States (Active)
Researchers
- Principal investigator: Jacobson, Daniel a — Research Triangle Institute
- Study coordinator: Jacobson, Daniel a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.