Identifying effective treatments for PTSD and substance use disorders
Official title: Advancing patient-centered research using meta-analysis of individual patient data to identify clinically significant trajectories of PTSD/SUD and recovery outcomes
Funded at Rutgers, the State Univ of N.j. · NIH-11161748 · Data updated 2026-11-12
This study is looking at how to help people with PTSD and substance use issues get better by using advanced methods to understand what treatments work best for them, so they can receive personalized care that fits their unique recovery journey.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rutgers, the State Univ of N.j. NIH-funded |
| Lab location | 1 site (Piscataway, United States) |
| Project start | June 1, 2025 |
| Project end | February 28, 2029 |
| Funding year | 2025 |
| Award (this year) | $882,816 |
| NIH project number | 1R01DA061338-01A1 |
| Project ID | NIH-11161748 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with PTSD and/or substance use disorders seeking treatment.
✕Less likely to help
Patients who do not have PTSD or substance use disorders may not receive any benefit from this research.
What this research studies
This research investigates how to improve treatment outcomes for individuals suffering from posttraumatic stress disorder (PTSD) and substance use disorders (SUD) by analyzing individual patient data. The study aims to address previous limitations in treatment evidence by using advanced statistical methods to better understand the effectiveness of various treatment approaches. By focusing on both substance use reduction and psychosocial recovery, the research seeks to provide a more comprehensive view of what successful treatment looks like for patients. Patients may benefit from tailored treatment recommendations based on their unique recovery trajectories.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment options for patients with PTSD and substance use disorders.
How similar studies have gone: Previous research using similar meta-analytic approaches has shown promise in improving treatment outcomes for various mental health conditions.
Where this research is happening
-
Rutgers, the State Univ of N.j.
Piscataway, United States Active
Researchers
- Principal investigator: Hien, Denise Aimee — Rutgers, the State Univ of N.j.
- Study coordinator: Hien, Denise Aimee
Related research
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-
Transdiagnostic Behavior Therapy for Veterans with Social Anxiety and PTSD Symptoms
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.