Identifying early signs of worsening psychotic symptoms in youth
Predicting Attenuated Psychotic Symptoms Amongst Youth Endorsing Persistent Distressing Psychotic-like Experiences
This study is looking at how early life experiences and surroundings might help us figure out which young people are more likely to develop serious symptoms of psychosis, so we can find ways to prevent it before it becomes a bigger issue.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-11107785 on NIH RePORTER |
What this research studies
This research investigates how certain early experiences and environmental factors can predict the development of more severe psychotic symptoms in young people. By analyzing data from the Adolescent Brain Cognitive Development (ABCD) study, the researchers aim to identify reliable indicators that can help in early screening and prevention of psychosis. The study focuses on youth who have experienced psychotic-like experiences and seeks to understand which individuals are at higher risk of developing attenuated psychotic symptoms. The goal is to develop effective prevention strategies before significant functional decline occurs.
Who could benefit from this research
Good fit: Ideal candidates for this research are youth aged 0-21 who have experienced psychotic-like experiences.
Not a fit: Patients who do not have any history of psychotic-like experiences may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier identification and intervention for youth at risk of developing severe psychotic disorders.
How similar studies have performed: Previous research has shown promise in early identification and intervention strategies for psychosis, but this specific approach is novel and aims to fill existing gaps in understanding.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Karcher, Nicole R. — Washington University
- Study coordinator: Karcher, Nicole R.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.