Identifying early signs of sepsis in critically ill ICU patients
Sepsis Physiomarkers for Appropriate Risk Knowledge of monitored patients in the ICU (SPARK-ICU)
This study is looking at how we can use real-time health data to better predict sepsis in critically ill patients in the ICU, so doctors can catch it early and improve care for those at risk.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10875604 on NIH RePORTER |
What this research studies
This research focuses on critically ill patients in the ICU who are at risk of developing sepsis, a severe infection that can significantly increase mortality rates. The study aims to develop new 'physiomarkers' from continuous physiological data, which can help predict the onset of sepsis more accurately than traditional methods that rely on structured electronic medical records. By utilizing real-time data streams and advanced machine learning algorithms, the research seeks to provide timely alerts to healthcare providers, potentially improving patient outcomes. The goal is to create a more reliable and efficient system for monitoring patients at risk of sepsis.
Who could benefit from this research
Good fit: Ideal candidates for this research are critically ill patients aged 21 and older who are admitted to the ICU and at risk of developing sepsis.
Not a fit: Patients who are not critically ill or those who do not require ICU admission may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and intervention for sepsis, significantly reducing mortality rates among critically ill patients.
How similar studies have performed: Previous research has shown promise in using machine learning and continuous data monitoring for predicting sepsis, indicating that this approach has potential for success.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Kamaleswaran, Rishikesan — Duke University
- Study coordinator: Kamaleswaran, Rishikesan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.