Identifying early signs of cerebral adrenoleukodystrophy in children
Neurocognitive and neuroimaging markers of emerging cerebral adrenoleukodystrophy
This study is looking at how adrenoleukodystrophy (ALD) affects kids' brains so we can find early signs that help us catch the condition before it causes serious damage, making it easier to treat.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-10876944 on NIH RePORTER |
What this research studies
This research focuses on understanding how adrenoleukodystrophy (ALD), a serious neurological disorder, affects children's brains. It aims to identify early neurocognitive and neuroimaging markers that can predict the onset of cerebral ALD, which can lead to severe brain damage if not treated promptly. By utilizing advanced neuroimaging techniques and statistical methods, the research seeks to develop new assessments that can help detect ALD early, allowing for timely intervention. The project is supported by a team of experts at the University of Minnesota, providing the necessary training for the principal investigator to conduct this important work.
Who could benefit from this research
Good fit: Ideal candidates for this research are boys diagnosed with adrenoleukodystrophy, particularly those identified through newborn screening programs.
Not a fit: Patients who do not have adrenoleukodystrophy or those who are not within the pediatric age range may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and treatment of cerebral ALD, potentially preventing irreversible cognitive decline in affected children.
How similar studies have performed: Previous research has shown promise in using neuroimaging techniques to identify neurological conditions early, suggesting that this approach could be effective for ALD as well.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Pierpont, Elizabeth Irene — University of Minnesota
- Study coordinator: Pierpont, Elizabeth Irene
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.