Identifying early signs of breast cancer using advanced biological techniques
Official title: Quantifying early biomarkers of mammary carcinogenesis with multiplexed spatial biology
Funded at Silent Spring Institute · NIH-11076837 · Data updated 2026-11-12
This study is looking for early signs that might show if someone is at risk for breast cancer by checking how certain chemicals affect the body, using lab tests with rodents to learn more about these effects, and it hopes to help improve ways to prevent cancer in the future.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Silent Spring Institute NIH-funded |
| Lab location | 1 site (Newton, United States) |
| Project start | April 22, 2024 |
| Project end | March 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $156,055 |
| NIH project number | 5K01ES036182-02 |
| Project ID | NIH-11076837 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals at higher risk for breast cancer, particularly those with a family history or known exposure to harmful chemicals.
✕Less likely to help
Patients who are not at risk for breast cancer or those who do not have a history of chemical exposure may not benefit from this research.
What this research studies
This research focuses on discovering early biomarkers that indicate the risk of developing breast cancer by examining the effects of chemical exposures. The approach integrates both experimental and observational studies, utilizing rodent models to explore how certain chemicals may lead to cancer through mechanisms like genotoxicity and endocrine disruption. By employing innovative multiplexed spatial biology methods, the research aims to provide a deeper understanding of the interactions between these factors and their implications for breast cancer risk. This work not only seeks to advance scientific knowledge but also aims to inform future cancer prevention strategies.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for early detection and prevention of breast cancer, potentially saving lives.
How similar studies have gone: Previous research has shown promise in identifying biomarkers for cancer risk, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Silent Spring Institute
Newton, United States Active
Researchers
- Principal investigator: Kay, Jennifer Elizabeth — Silent Spring Institute
- Study coordinator: Kay, Jennifer Elizabeth
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.