Identifying early signs of behavior issues in at-risk infants

Characterizing early signs of neurobehavioral dysregulation in infants at increased risk for behavioral disorders

NIH-funded research Duke University · NIH-11052927

This study is looking at how to spot early signs of behavior challenges in babies who might be at risk, especially those exposed to nicotine before birth, so we can help them get the right support as they grow.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionDuke University NIH-funded
Lab location1 site (Durham, United States)
Project IDNIH-11052927 on NIH RePORTER

What this research studies

This research focuses on understanding the early signs of neurobehavioral dysregulation in infants who are at increased risk for behavioral disorders, particularly those exposed to prenatal nicotine. By examining various developmental factors such as attention, motor skills, and sleep patterns, the study aims to identify infants who may be more likely to develop persistent behavioral issues like ADHD. The approach involves using advanced methodologies to categorize these infants into distinct risk groups, which could lead to more tailored interventions. The research will utilize multiple constructs to assess behavior and development over time.

Who could benefit from this research

Good fit: Ideal candidates for this research include infants under 1 year of age who have been exposed to prenatal nicotine or exhibit early signs of behavioral dysregulation.

Not a fit: Patients who are older than 3 years or do not have any identified risk factors for behavioral disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier identification and intervention for infants at risk of developing behavioral disorders, potentially improving long-term outcomes.

How similar studies have performed: Previous research has shown promise in identifying early behavioral markers in at-risk populations, suggesting that this approach could yield valuable insights.

Where this research is happening

Durham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Attention deficit hyperactivity disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.