Identifying early signs of Alzheimer's disease through cognitive tasks.
Novel Cognitive Markers of Early Alzheimer's Disease.
This study is looking at some simple brain tasks to help spot early signs of Alzheimer's disease in people who might be at risk, even before they show any symptoms, so we can better understand and track changes in their thinking skills.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10840886 on NIH RePORTER |
What this research studies
This research investigates new cognitive tasks designed to detect early signs of Alzheimer's disease before clinical symptoms appear. By focusing on two specific tasks, Visual Sensory Binding (VSB) and Visual Short Term Memory Binding (VSTMB), the study aims to provide a better understanding of cognitive decline in individuals who show biomarkers for Alzheimer's. These tasks are intended to be easy to administer and could help in staging the disease more effectively. The goal is to create a 'cognitive stress test' that can predict future cognitive decline in patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults who show biomarkers for Alzheimer's disease but do not yet exhibit clinical symptoms.
Not a fit: Patients who are not showing any biomarkers for Alzheimer's disease or who have advanced Alzheimer's symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate detection of Alzheimer's disease, allowing for timely interventions.
How similar studies have performed: Previous research has shown promise in using cognitive tasks to detect dementia, suggesting that this approach may be effective.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Jacobs, Diane M. — University of California, San Diego
- Study coordinator: Jacobs, Diane M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.