Identifying early risk of preeclampsia using blood tests
Epigenetic phenotyping from liquid biopsy for preeclampsia risk classification during the first trimester
This study is looking at how to identify the risk of preeclampsia early in pregnancy by checking the mother's blood for certain genetic markers, which could help doctors take action sooner and improve health for both moms and babies.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Kanona, INC. NIH-funded |
| Lab location | 1 site (Scotch Plains, United States) |
| Project ID | NIH-10822733 on NIH RePORTER |
What this research studies
This research investigates how to classify the risk of preeclampsia, a serious pregnancy condition, during the first trimester by analyzing genetic material found in the mother's blood. The approach involves examining circulating placental derivatives, such as RNA and cell-free DNA, to detect early signs of complications. By improving risk assessment methods, the research aims to enhance early intervention strategies, potentially leading to better outcomes for both mothers and their babies.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant individuals in their first trimester who may be at risk for developing preeclampsia.
Not a fit: Patients who are not pregnant or those who are in later stages of pregnancy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier identification of women at risk for preeclampsia, allowing for timely interventions that could improve maternal and fetal health.
How similar studies have performed: Other research has shown promise in using similar approaches to assess pregnancy complications, indicating potential for success in this area.
Where this research is happening
Scotch Plains, United States
- Kanona, INC. — Scotch Plains, United States (Active)
Researchers
- Principal investigator: Reichel, Jonathan — Kanona, INC.
- Study coordinator: Reichel, Jonathan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.