Identifying early brain and behavior indicators of tic disorders in children

Preschool MRI predictors of tic outcomes from a 15-year longitudinal study

NIH-funded research Washington University · NIH-11019824

This study is looking at how brain scans and behavior tests can help us understand if kids might develop tic disorders like Tourette syndrome as they grow up, so we can better support them and their families.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWashington University NIH-funded
Lab location1 site (Saint Louis, United States)
Project IDNIH-11019824 on NIH RePORTER

What this research studies

This research investigates how early brain imaging and behavioral assessments can predict the development of tic disorders, such as Tourette syndrome, in children. By analyzing data collected over 15 years from a diverse group of children, the study aims to differentiate between brain features that precede tics and those that result from them. Participants will undergo video assessments and complete surveys about their tic experiences as they transition into young adulthood. The goal is to provide insights that could help in understanding individual prognoses for tic disorders.

Who could benefit from this research

Good fit: Ideal candidates for this research include children aged 3 to 19 who have participated in the Preschool Depression Study and may or may not exhibit tic symptoms.

Not a fit: Patients who do not have a history of tic disorders or related behavioral issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved early identification and management strategies for children at risk of developing tic disorders.

How similar studies have performed: Previous research has shown promise in using brain imaging and behavioral assessments to predict neurological conditions, suggesting that this approach may yield valuable insights.

Where this research is happening

Saint Louis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.