Identifying disease subtypes for personalized treatment in asthma and breast cancer.
Official title: Disease subtyping guided by clinical phenotype for precision medicine
Funded at University of Pittsburgh at Pittsburgh · NIH-10987019 · Data updated 2026-11-12
This study is looking to better understand different types of asthma in kids and breast cancer by combining various health data, so that doctors can offer more personalized treatments that fit each patient's unique needs.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project start | February 3, 2023 |
| Project end | November 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $274,485 |
| NIH project number | 5R01LM014142-03 |
| Project ID | NIH-10987019 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include children with asthma and adults diagnosed with breast cancer who are seeking more tailored treatment options.
✕Less likely to help
Patients with conditions unrelated to asthma or breast cancer may not receive any benefit from this research.
What this research studies
This research aims to improve the classification of diseases like asthma in children and breast cancer by integrating various types of biological data and clinical information. By using advanced clustering techniques, the study seeks to identify disease subtypes that are not only scientifically relevant but also clinically actionable. This means that the findings could lead to more tailored treatment options for patients based on their specific disease characteristics. The research will validate these methods through real-world applications in pediatric asthma and breast cancer.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatment strategies for patients with asthma and breast cancer.
How similar studies have gone: Previous research has shown promise in using similar outcome-guided approaches for disease subtyping, indicating potential for success in this novel application.
Where this research is happening
-
University of Pittsburgh at Pittsburgh
Pittsburgh, United States Active
Researchers
- Principal investigator: Tseng, George C. — University of Pittsburgh at Pittsburgh
- Study coordinator: Tseng, George C.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.