Identifying different types of pneumonia based on lung biology
Official title: Sub-phenotyping pneumonia by lung pathobiology
Funded at Boston University Medical Campus · NIH-10934340 · Data updated 2026-11-12
This study is looking at how different types of pneumonia affect the lungs in older patients to find out if certain groups of patients might respond better to specific treatments, with the hope of creating more personalized care for those with pneumonia.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 1, 2023 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $63,970 |
| NIH project number | 5F32HL170650-02 |
| Project ID | NIH-10934340 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include elderly individuals who have experienced pneumonia, particularly those with severe cases.
✕Less likely to help
Patients with pneumonia who are not elderly or those with mild cases may not benefit from this research.
What this research studies
This research investigates the various biological responses in the lungs of pneumonia patients to identify distinct sub-phenotypes that may respond differently to treatments. By analyzing autopsy samples from elderly patients who died from pneumonia, the study aims to uncover the complex immune responses and lung pathology associated with these sub-phenotypes. Additionally, it compares findings from human samples to those from mouse models to determine how well these models represent human pneumonia characteristics. This approach could lead to more personalized treatment strategies for pneumonia patients.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options tailored to the specific type of pneumonia a patient has.
How similar studies have gone: Other research has shown promise in characterizing pneumonia sub-phenotypes, but this specific approach using human autopsy samples is relatively novel.
Where this research is happening
-
Boston University Medical Campus
Boston, United States Active
Researchers
- Principal investigator: Hiller, Bradley — Boston University Medical Campus
- Study coordinator: Hiller, Bradley
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.