Identifying different types of alcohol use disorder through brain imaging and genetics
Mass Multivariate Derivation and Validation of AUD Biotypes using Developmental Imaging and Genomic Approaches
['FUNDING_CAREER'] · WASHINGTON UNIVERSITY · NIH-10894767
This study is looking to find different types of alcohol use disorder by analyzing brain scans and genetic information from people of all ages, so we can create more personalized treatment options that fit each person's unique needs.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WASHINGTON UNIVERSITY (nih funded) |
| Locations | 1 site (SAINT LOUIS, UNITED STATES) |
| Trial ID | NIH-10894767 on ClinicalTrials.gov |
What this research studies
This research aims to better understand alcohol use disorder (AUD) by identifying distinct biological subtypes of the condition. Using advanced machine learning techniques, the study will analyze brain imaging data and genetic information from a large group of participants ranging from childhood to older adulthood. By examining how these subtypes manifest across different ages and their relationship with behaviors like impulsivity and negative emotions, the research seeks to uncover personalized treatment options for AUD. The findings could lead to more effective interventions tailored to individual needs based on their specific AUD biotype.
Who could benefit from this research
Good fit: Ideal candidates for participation include individuals of all ages, from children to older adults, who are affected by alcohol use disorder or are at risk of developing it.
Not a fit: Patients who do not have alcohol use disorder or are not at risk may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective, personalized treatments for individuals suffering from alcohol use disorder.
How similar studies have performed: Other research has shown promise in using machine learning and genetic approaches to understand complex disorders, suggesting that this approach could yield valuable insights.
Where this research is happening
SAINT LOUIS, UNITED STATES
- WASHINGTON UNIVERSITY — SAINT LOUIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HATOUM, ALEXANDER S — WASHINGTON UNIVERSITY
- Study coordinator: HATOUM, ALEXANDER S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.