Identifying dangerous brain aneurysms using blood tests
Development of a Molecular Diagnostic to Identify Dangerous Intracranial Aneurysms
['FUNDING_SBIR_2'] · NEUROVASCULAR DIAGNOSTICS, INC. · NIH-10912433
This study is working on a new blood test to help doctors find dangerous brain aneurysms that might burst, making it easier and safer to decide which ones need urgent treatment and which can be watched over time.
Quick facts
| Phase | ['FUNDING_SBIR_2'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NEUROVASCULAR DIAGNOSTICS, INC. (nih funded) |
| Locations | 1 site (BUFFALO, UNITED STATES) |
| Trial ID | NIH-10912433 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a blood-based diagnostic tool to identify dangerous intracranial aneurysms (IAs) that have a high risk of rupture. Currently, clinicians rely on invasive imaging techniques to assess the risk of IAs, which can be costly and carry significant risks. By analyzing biological markers in blood samples, this study aims to provide a safer and more accurate method for determining which aneurysms require immediate treatment and which can be monitored over time. This approach could lead to better patient management and outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with unruptured intracranial aneurysms who are at risk of rupture.
Not a fit: Patients with ruptured aneurysms or those without any diagnosed aneurysms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the ability to identify high-risk aneurysms, potentially reducing mortality and disability rates associated with aneurysm ruptures.
How similar studies have performed: While there have been advancements in imaging techniques for aneurysm assessment, the development of a blood-based diagnostic tool for this purpose is a novel approach that has not been widely tested.
Where this research is happening
BUFFALO, UNITED STATES
- NEUROVASCULAR DIAGNOSTICS, INC. — BUFFALO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: POPPENBERG, KERRY — NEUROVASCULAR DIAGNOSTICS, INC.
- Study coordinator: POPPENBERG, KERRY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.