NIH-funded research NIH-funded research

Identifying colorectal cancer patients in South Africa who may not seek oncology care

Official title: A clinical prediction rule for identifying South African colorectal cancer patients who will fail to engage in oncology care

Funded at University of Kwazulu-Natal · NIH-10919199 · Data updated 2026-11-12

This study is looking to find out which new colorectal cancer patients in South Africa might have trouble getting the treatment they need, so doctors can better support those who need extra help.

More Colorectal Cancer research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Kwazulu-Natal
NIH-funded
Lab location1 site (Durban, South Africa)
Project startSeptember 2, 2021
Project endAugust 31, 2026
Funding year2024
Award (this year)$57,099
NIH project number5K43CA268978-04
Project IDNIH-10919199 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are newly diagnosed colorectal cancer patients in South Africa, particularly those in the public healthcare sector.

Less likely to help

Patients who are not newly diagnosed with colorectal cancer or those already engaged in oncology care may not benefit from this research.

What this research studies

This research aims to develop a clinical prediction rule to identify newly diagnosed colorectal cancer patients in South Africa who are at high risk of failing to engage in oncology care. By analyzing data from a cohort of patients and utilizing machine learning techniques, the study seeks to pinpoint specific predictors that indicate which patients may struggle to access necessary treatment. This targeted approach will help healthcare providers focus their resources on those who need it most, improving overall patient management in a resource-constrained environment.

Why it matters

Potential benefit: If successful, this research could lead to improved access to oncology care for high-risk colorectal cancer patients in South Africa.

How similar studies have gone: Similar approaches using clinical prediction rules have shown promise in other healthcare settings, indicating potential for success in this novel application.

Where this research is happening

  • University of Kwazulu-Natal
    Durban, South Africa
    Active

Researchers

  • Principal investigator: Moodley, Yoshan — University of Kwazulu-Natal
  • Study coordinator: Moodley, Yoshan

Related research

Other NIH-funded projects on the same topics.

  • Improving colorectal cancer screening and follow-up care.

    This study is working to help more people get screened for colorectal cancer and receive the follow-up care they need, especially those who haven't been screened much before, so that everyone can have better access to important health checks and improve their overall health.

    NIH research Research Triangle Institute · Research Triangle Park, United States · NIH-9627071

  • Colorectal cancer prognosis through a broad, collaborative study

    A large, multi-center study follows people newly diagnosed with colorectal cancer to find biomarkers and patterns that predict outcomes and guide future care.

    NIH research Utah State Higher Education System--University of Utah · Salt Lake City, United States · NIH-11590756

  • Ceramides and how they affect metabolism and colorectal cancer in adults

    A study in adults with obesity-related health issues will explore how a fat-related molecule called ceramide influences metabolic problems and colorectal cancer risk.

    NIH research Utah State Higher Education System--University of Utah · Salt Lake City, United States · NIH-11535283

  • Automated point-of-care DNA methylation test for colorectal cancer in LMICs

    A fast, affordable blood test using DNA markers to help identify people at higher risk of colorectal cancer in low- and middle-income countries.

    NIH research Johns Hopkins University · Baltimore, United States · NIH-11531863

  • Rewiring Colorectal Cancer to Harness Therapeutic Hyperactivation

    A Yale team is exploring brain-storming new ways to treat colorectal cancer by safely boosting certain cancer signaling pathways to kill cancer cells and by reshaping cancer cell states to improve responses to existing therapies.

    NIH research Yale University · New Haven, United States · NIH-11505210

  • Comparative modeling to guide colorectal cancer screening and care

    A researcher team will use computer models to study how access to care, risk, and new screening options affect colorectal cancer outcomes and costs for adults in the US.

    NIH research Utah State Higher Education System--University of Utah · Salt Lake City, United States · NIH-11495363

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.