NIH-funded research NIH-funded research

Identifying cancer promotion signals to improve prevention strategies

Official title: PROMINENT: Discovering the molecular signatures of cancer PROMotion to INform prevENTion

Funded at Imperial College of Science, Technology and Medicine · NIH-10912837 · Data updated 2026-11-12

This study is looking at the tiny changes in our cells that can lead to cancer, hoping to find clues that help us prevent it, so that patients can get personalized advice on how to lower their risk based on their unique biology.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionImperial College of Science, Technology and Medicine
NIH-funded
Lab location1 site (London, United Kingdom)
Project startAugust 23, 2023
Project endMay 31, 2026
Funding year2023
Award (this year)$107,654
NIH project number1OT2CA290880-01
Project IDNIH-10912837 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals at high risk for cancer due to genetic, environmental, or lifestyle factors.

Less likely to help

Patients who are not at risk for cancer or those with established cancer diagnoses may not receive benefit from this research.

What this research studies

This research investigates the molecular signatures that contribute to the promotion of cancer, aiming to uncover specific biological markers that can inform prevention strategies. By analyzing various biological samples, the research seeks to understand how these molecular signatures influence cancer development. Patients may benefit from this research as it could lead to more targeted prevention measures based on individual risk factors identified through these signatures.

Why it matters

Potential benefit: If successful, this research could provide patients with personalized prevention strategies that significantly reduce their risk of developing cancer.

How similar studies have gone: Previous research has shown promise in identifying molecular signatures related to cancer, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Imperial College of Science, Technology and Medicine
    London, United Kingdom
    Active

Researchers

  • Principal investigator: Gunter, Marc James — Imperial College of Science, Technology and Medicine
  • Study coordinator: Gunter, Marc James

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.