Identifying brain signals to predict epilepsy after traumatic brain injury

EEG and MRI Biomarkers to Predict Post-traumatic Epilepsy

['FUNDING_OTHER'] · YALE UNIVERSITY · NIH-10864951

This study is looking for early signs in brain scans and brain wave patterns that can help predict if someone who has had a traumatic brain injury might develop epilepsy later on, so we can better support their recovery and quality of life.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorYALE UNIVERSITY (nih funded)
Locations1 site (NEW HAVEN, UNITED STATES)
Trial IDNIH-10864951 on ClinicalTrials.gov

What this research studies

This research focuses on finding early biomarkers using EEG and MRI to predict the development of post-traumatic epilepsy in patients who have suffered a traumatic brain injury (TBI). By analyzing neurophysiologic and neuroimaging data, the study aims to identify patients at high risk for this complication, which can significantly impact their recovery and quality of life. The research involves advanced techniques in signal processing and machine learning to enhance the understanding of brain injuries and their long-term effects. Ultimately, the goal is to improve patient monitoring and facilitate the development of targeted treatments to prevent epilepsy.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have recently experienced a traumatic brain injury and are at risk for post-traumatic epilepsy.

Not a fit: Patients who have not experienced a traumatic brain injury or those with pre-existing epilepsy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better monitoring and treatment options for patients at risk of developing post-traumatic epilepsy.

How similar studies have performed: Other research has shown promise in using neuroimaging and biomarker identification for similar conditions, indicating a potential for success in this approach.

Where this research is happening

NEW HAVEN, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired brain injury

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.