Identifying brain signal patterns to diagnose autism earlier
Temperodynamic neural variability as an early-emerging biomarker of autism spectrum disorders
This study is looking at how changes in brain activity during a child's first year can help spot signs of Autism Spectrum Disorder early on, so that kids can get the support they need sooner.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Virginia NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project ID | NIH-10904738 on NIH RePORTER |
What this research studies
This research investigates how variations in brain signals can serve as early indicators of Autism Spectrum Disorder (ASD) in children. By focusing on the first year of life, the study aims to identify neurobiological markers that can predict ASD before behavioral symptoms appear. The approach involves analyzing temperodynamic neural variability, which captures the brain's fluctuating nature, to develop precise diagnostic tools and treatment plans tailored to individual needs. This could lead to earlier interventions that significantly improve outcomes for affected children.
Who could benefit from this research
Good fit: Ideal candidates for this research include infants and young children under the age of 4 who are at risk for Autism Spectrum Disorder.
Not a fit: Patients who are older than 4 years or those who do not exhibit any risk factors for autism may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enable earlier diagnosis and intervention for children with autism, leading to better developmental outcomes.
How similar studies have performed: Other research has shown promise in identifying neurobiological markers for autism, but this specific approach using temperodynamic neural variability is relatively novel.
Where this research is happening
Charlottesville, United States
- University of Virginia — Charlottesville, United States (Active)
Researchers
- Principal investigator: Puglia, Meghan H — University of Virginia
- Study coordinator: Puglia, Meghan H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.