Identifying brain networks to predict treatment resistance and surgical outcomes in epilepsy
Identifying brain networks to predict treatment resistance and post-surgical outcome: An ENIGMA-Epilepsy initiative
This study is looking at how certain brain patterns can help doctors figure out which epilepsy patients will do well with medications or surgery, using special imaging techniques to spot hidden brain issues, so they can create more personalized treatment plans just for you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10849658 on NIH RePORTER |
What this research studies
This research investigates how specific brain networks can be identified to predict which epilepsy patients will respond to anti-seizure medications or benefit from surgery. By utilizing advanced imaging techniques like structural MRI and diffusion-weighted imaging, the study aims to uncover subtle brain abnormalities that may not be visible in standard scans. The goal is to gather extensive clinical and genetic data from a diverse group of patients to improve diagnostic accuracy and treatment planning. This could ultimately help tailor therapies to individual patients based on their unique brain characteristics.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 65 and older who have epilepsy and are experiencing treatment resistance or are being considered for surgical intervention.
Not a fit: Patients with epilepsy who respond well to anti-seizure medications and do not require surgical evaluation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatment strategies for epilepsy patients, reducing the number of individuals who do not respond to current therapies.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques to identify brain abnormalities in epilepsy, suggesting that this approach could yield valuable insights.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Mcdonald, Carrie R — University of California, San Diego
- Study coordinator: Mcdonald, Carrie R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.