Identifying brain markers to improve depression treatment selection
Establishing Multimodal Brain Biomarkers Using Data-driven Analyticsfor Treatment Selection in Depression
This study is looking to create smart tools that use brain scans to help figure out which depression treatments might work best for you, so you can get the right help faster and with less guesswork.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Lehigh University NIH-funded |
| Lab location | 1 site (Bethlehem, United States) |
| Project ID | NIH-11042272 on NIH RePORTER |
What this research studies
This research aims to develop advanced analytical tools that utilize machine learning and large-scale neuroimaging data to identify brain biomarkers associated with treatment responses in patients with depression. By analyzing data from functional magnetic resonance imaging (fMRI) and electroencephalography (EEG), the project seeks to uncover neurobiological patterns that can predict how well patients will respond to antidepressant medications. This approach aims to reduce the trial-and-error process often involved in finding effective treatments, ultimately leading to faster and more personalized care for individuals suffering from depression.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with major depression who are seeking treatment options.
Not a fit: Patients with depression who are not interested in medication or those with treatment-resistant depression may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment options for patients with depression, improving their chances of recovery.
How similar studies have performed: Previous research has shown promise in using neuroimaging and machine learning to identify biomarkers for various mental health conditions, suggesting that this approach could yield valuable insights for depression treatment as well.
Where this research is happening
Bethlehem, United States
- Lehigh University — Bethlehem, United States (Active)
Researchers
- Principal investigator: Zhang, Yu — Lehigh University
- Study coordinator: Zhang, Yu
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.