Identifying brain markers that predict psychosis in adolescents
Discovering prognostic neuroimaging biomarkers of the psychosis spectrum using network control theory
This study is looking at how changes in brain development might lead to conditions like schizophrenia in teenagers, and it aims to find early signs that could help identify those at risk so that we can offer support before symptoms appear.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rutgers Biomedical and Health Sciences NIH-funded |
| Lab location | 1 site (Newark, UNITED STATES) |
| Project ID | NIH-10757468 on NIH RePORTER |
What this research studies
This research investigates how disruptions in brain development can lead to psychosis, such as schizophrenia, in adolescents. By using advanced techniques from network neuroscience and machine learning, the study aims to identify specific brain abnormalities that may predict the onset of psychotic symptoms years before they occur. The research will analyze large datasets of neuroimaging and clinical information to uncover these prognostic biomarkers, with a focus on understanding how these factors may differ between sexes. Ultimately, the goal is to enable early intervention strategies that could reduce the risk of developing psychosis.
Who could benefit from this research
Good fit: Ideal candidates for this research are adolescents who may be at risk for developing psychotic disorders based on family history or early symptoms.
Not a fit: Patients who are already experiencing severe psychotic symptoms or those outside the adolescent age range may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier identification and intervention for individuals at risk of developing psychosis, potentially improving long-term outcomes.
How similar studies have performed: Other research has shown promise in using neuroimaging and machine learning to identify biomarkers for mental health conditions, suggesting that this approach could be effective.
Where this research is happening
Newark, UNITED STATES
- Rutgers Biomedical and Health Sciences — Newark, United States (Active)
Researchers
- Principal investigator: Parkes, Linden — Rutgers Biomedical and Health Sciences
- Study coordinator: Parkes, Linden
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.