Identifying brain markers of resilience in extremely preterm children
Towards biomarkers of resiliency in the extremely preterm child: a multimodal neuroimaging study of brain and environment
This study is looking at how very premature children can still develop good language skills, even if they face challenges, by examining their brain connections and the impact of their surroundings, and it compares them to full-term children to find out what helps them succeed.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cincinnati Childrens Hosp Med Ctr NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project ID | NIH-10869987 on NIH RePORTER |
What this research studies
This research investigates how extremely preterm children, who are at risk for neurocognitive impairments, can still achieve positive language outcomes. By using advanced neuroimaging techniques, the study aims to identify brain-based markers of resilience in these children while considering their environmental influences. The research will compare a group of extremely preterm children with no overt brain injury to term children, focusing on their brain connectivity and its relationship to language development. The goal is to understand how certain neural adaptations may help these children thrive despite their early challenges.
Who could benefit from this research
Good fit: Ideal candidates for this research are extremely preterm children (born at less than 28 weeks gestation) who are currently performing within normal limits on language tasks.
Not a fit: Patients who are not extremely preterm or who have significant brain injuries may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prognostic tools and interventions that support language development in extremely preterm children.
How similar studies have performed: Previous research has shown promising results in identifying neuroimaging markers related to cognitive outcomes in similar populations, suggesting that this approach may yield valuable insights.
Where this research is happening
Cincinnati, United States
- Cincinnati Childrens Hosp Med Ctr — Cincinnati, United States (Active)
Researchers
- Principal investigator: Barnes-Davis, Maria E — Cincinnati Childrens Hosp Med Ctr
- Study coordinator: Barnes-Davis, Maria E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.