Identifying brain markers for problematic cannabis use

Connectome-based neuromarkers of problem cannabis use

NIH-funded research Yale University · NIH-10891574

This study is looking at how certain brain features might help us understand why some teens and young adults have problems with cannabis use, so we can find ways to help those at risk before issues arise.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionYale University NIH-funded
Lab location1 site (New Haven, United States)
Project IDNIH-10891574 on NIH RePORTER

What this research studies

This research investigates the brain-based risk factors associated with problematic cannabis use, particularly in adolescents and young adults. By utilizing advanced neuroimaging techniques and machine learning, the study aims to identify specific neural networks that predict the likelihood of developing issues related to cannabis use. The research combines data from large-scale studies, including a nationally representative sample of children, to understand how these brain markers develop over time and their relationship with other addiction risk factors. This approach seeks to enhance early intervention strategies for those at risk.

Who could benefit from this research

Good fit: Ideal candidates for this research include adolescents and young adults, particularly those with a family history of substance use or exposure to early adversity.

Not a fit: Patients who do not use cannabis or have no history of substance use issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved prevention and intervention strategies for individuals at risk of cannabis-related harm.

How similar studies have performed: Previous research has shown promise in identifying brain markers for various substance use disorders, suggesting that this approach may yield valuable insights.

Where this research is happening

New Haven, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.