Identifying brain injury markers in adults with sickle cell disease
Biomarkers of ischemic brain injury in adults with sickle cell disease
['FUNDING_R01'] · VANDERBILT UNIVERSITY MEDICAL CENTER · NIH-11018577
This study is looking at how sickle cell disease impacts the brain in adults, aiming to find signs that show if someone is at risk for strokes, so we can create better ways to keep you healthy and prevent complications.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | VANDERBILT UNIVERSITY MEDICAL CENTER (nih funded) |
| Locations | 1 site (NASHVILLE, UNITED STATES) |
| Trial ID | NIH-11018577 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how sickle cell disease affects the brain, particularly looking for biomarkers that indicate brain injury and the risk of stroke in adults. By studying these biomarkers, the research aims to develop better screening tools to identify adults at risk for strokes and other complications associated with sickle cell disease. The approach involves a longitudinal study where patients will be assessed over time to evaluate their brain health and response to treatments. This could lead to improved care and prevention strategies for adults living with this condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with sickle cell disease who are at risk for stroke and other brain complications.
Not a fit: Patients without a diagnosis of sickle cell disease or those who are not adults may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better identification and prevention of strokes in adults with sickle cell disease, ultimately improving their quality of life.
How similar studies have performed: Previous research has shown promise in identifying biomarkers for stroke risk in other populations, suggesting that this approach may yield valuable insights for adults with sickle cell disease.
Where this research is happening
NASHVILLE, UNITED STATES
- VANDERBILT UNIVERSITY MEDICAL CENTER — NASHVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: JORDAN, LORI CHAFFIN — VANDERBILT UNIVERSITY MEDICAL CENTER
- Study coordinator: JORDAN, LORI CHAFFIN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.