Identifying brain connectivity markers to predict treatment response in focal epilepsy
MRI Connectivity Biomarkers of Treatment Response in Focal Epilepsy
This study is looking at how the connections in your brain might help doctors predict how well you'll respond to epilepsy treatments, like medications or surgery, so they can find the best option for you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-10794219 on NIH RePORTER |
What this research studies
This research investigates how brain connectivity patterns can serve as early indicators of how well patients with focal epilepsy will respond to anti-epileptic medications or surgical interventions. By using advanced MRI techniques, the study aims to quantify the functional and structural connectivity in the brains of patients with temporal lobe epilepsy. The goal is to improve treatment outcomes by identifying which patients are likely to benefit from specific therapies based on their brain connectivity profiles.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with drug-resistant temporal lobe epilepsy who have not responded to standard anti-epileptic medications.
Not a fit: Patients with well-controlled epilepsy or those whose seizures are not focal in nature may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized treatment plans for patients with focal epilepsy, improving their chances of achieving seizure freedom.
How similar studies have performed: Previous research has shown promise in using brain connectivity as a predictor of treatment outcomes in epilepsy, suggesting that this approach could yield valuable insights.
Where this research is happening
Nashville, United States
- Vanderbilt University Medical Center — Nashville, United States (Active)
Researchers
- Principal investigator: Morgan, Victoria L — Vanderbilt University Medical Center
- Study coordinator: Morgan, Victoria L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.